Prostate cancer is the most frequently diagnosed cancer in 112 countries and the leading cause of cancer death in 48 countries.[1] It is the fifth leading cause of male cancer-related deaths worldwide, with more than 1.4 million newly diagnosed cases and 375,304 deaths reported annually.[2]
PSA 10 to 20 ng/ml. This means your cancer is likely to grow slowly and unlikely to spread. Your treatment options may include active surveillance, surgery or radiotherapy with hormone therapy. CPG 3. Gleason score 3 + 4 = 7 (grade group 2), and; PSA 10 to 20 ng/ml, and; T stage of 1 or 2. You will also be in this group if you have:
When total PSA concentration is above 10.0 ng/mL, the probability of cancer is high and prostate biopsy is generally recommended. The total PSA range of 4.0 to 10.0 ng/mL has been described as a diagnostic "gray zone," in which the free PSA:total PSA ratio helps to determine the relative risk of prostate cancer (see table).
To define a normal range for PSA values (ng/mL) by age and create a prediction model for prostate cancer incidence. We conducted a retrospective analysis using 263,073 observations of PSA values
The levels of prostate-specific antigen in the blood can indicate further testing is needed to screen for cancer. Over the age of 70, men in exceptional health should have a discussion with their doctor about whether PSA testing makes sense for them. Levels above 10.0 ng/mL are considered to be far above the studied normal range.
PSA is a protein your prostate gland produces. High levels of PSA circulating in your blood may indicate prostate cancer, but not always. The recommended upper limits for PSA levels by age are as follows: Age (years) PSA upper limit (ng/mL) 40-49 2.5 50-59 3.5 60-69 4.5 70-79 6.5. Learn more about how your PSA levels may differ based on your age and other factors.
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psa normal range by age